Table 1. Guanylate cyclase and cADPR antagonists suppress NO inactivation of I_K,in and [Ca²⁺]_i elevation.

Treatment	IK,in (pA)	[Ca2+]i resting (nM)	[Ca2+]i evoked (nM)
Control	-517 ± 53 (27)	159 ± 15 (6)	452 ± 31 (6)
10 μM SNAP	-151 ± 35 (27)	262 ± 31 (6)	741 ± 70 (6)
+1 μM ryanodine*	-535 ± 72 (5)	171 ± 11 (3)	200 ± 12 (3)
+20 μM ODQ	-443 ± 36 (5)	106 ± 26 (4)	303 ± 68 (4)

I_K,in is determined as described in the Fig. 2 legend, and [Ca²⁺]_i is determined as described in the Fig. 4 legend. Data are from n cells.

^*Partial block of evoked [Ca²⁺]_i increase reported previously (24) probably reflects the short (1-min) pretreatment used in these experiments