Figure 2.

Survival of naive and activated anti-H-Y T cells in antigen-free mice. (A) The recovery of B6.2.16 CD8⁺ cells was about three times greater in mice injected with naive compared with activated B6.2.16 CD8⁺ cells 70 days after the adoptive transfer of 1.5 × 10⁶ purified cells. (B) Limiting dilution analysis was used to determine the frequency of anti-H-Y CTL precursors (anti-H-Y CTL-P) in the recipient RAG1⁻TAP1⁺ mice analyzed in A. Similar results have been obtained in two independent experiments.