Figure 2.

Graphs on the left show that older, biotinylated cells expose more PS in both rabbit 1 (gray points and curves) and rabbit 2 (black points and curves). The parameters for our model of red cell senescence were chosen to provide a least-squares fit to these data on exposed PS in biotinylated cells (r² > 0.98). Graphs on the right show that the model correctly predicts the rate at which biotinylated cells are removed from circulation (r² > 0.97). This supports the model, which assumes that the amount of exposed PS is proportional to the rate of senescent death.