Table 1.

Isoflavonoid concentrations before and after purification of lipoprotein fractions by gel filtration following intake of one soy bar (12 mg of genistein, 7 mg of daidzein) three times daily for 1 week in a normolipidemic woman

Lipoprotein fraction	Gel filtration	Glucuronide fraction*		Free + sulfate fraction†
		Genistein, pmol/mg protein	Daidzein, pmol/mg protein	Genistein, pmol/mg protein	Daidzein, pmol/mg protein
VLDL	Before	53.3	27.1	0.52	0.83
	After	1.1 (<0.1%)	1.2 (<0.1%)	0.70 (0.5%)	0.00 (0%)
LDL	Before	8.44	1.98	0.31	0.31
	After	1.4 (0.1%)	3.8 (0.7%)	0.64 (2.1%)	0.76 (1.2%)
HDL	Before	3.92	1.8	0.15	0.29
	After	0.28 (<0.1%)	0.21 (<0.1%)	0.21 (1.2%)	0.00 (0%)
Total plasma		754 nmol/liter	406 nmol/liter	23.5 nmol/liter	49.2 nmol/liter

^*Percent values calculated from total plasma glucuronide level. 

^†Percent values calculated from total plasma free + sulfate level.