Table 2.
Pathogenicity of CVS-24, CVS-N2c, and CVS-B2c
| Virus | Pathogenicity index
|
|||||
|---|---|---|---|---|---|---|
| Neonate
|
Adult
|
|||||
| I.C. | I.M. | I.D. | I.C. | I.M. | I.D. | |
| CVS-24 | ND | ND | ND | 0.11 | 0.0000021 | ND |
| CVS-N2c | 0.85 | 0.00016 | 0.00018 | 0.52 | 0.0000081 | 0.00000191 |
| CVS-B2c | 1.77 | 0.00115 | 0.00023 | 0.28 | 0.0000029 | 0.00000004 |
Pathogenicity index was calculated by dividing the LD50 value per ml determined after inoculation by the virus titer (FFU/ml). Virus titers were determined in NA cells with the immunofluorescent test and the LD50 values were calculated. I.C., Intracranial; i.m., intramuscular; i.d., intradermal; ND, not determined.