Table 6.
Biophysical properties of zNav1.5 and zNav1.5 plus zβ1 (variant D) in CHO cells.
| Peak amplitude (pA)* | Activation V1/2(mV) | Inactivation V1/2(mV) | Recovery from inactivation, Tau (ms) | |
| zNav1.5 alone | -125.7 ± 16.9 pA/pF (n = 8) | -47.5 ± 1.6 mV (n = 8) | -79.3 ± 1.0 mV (n = 5) | 127.9 ± 8.1 ms (n = 4) |
| zNav1.5 + zβ1 | -211.1 ± 11.2 pA/pF† (n = 5) | -53.0 ± 2.5 mV† (n = 5) | -82.6 ± 1.1 mV† (n = 6) | 125.7 ± 4.1 ms (n = 6) |
All values are mean ± standard error of the mean (SEM). * at a -30 mV depolarizing pulse. † p < 0.001 vs. zNav1.5 alone, Student's T-Test. pA = picoamperes; mV = millivolts; ms = milliseconds; pF = picofahrads; V1/2 = half maximal voltage.