Figure 5. Clearance of the ST2 S. pneumoniae Strain from Wild-Type and Apcs ^−/− Mice Inoculated Intravenously with 1.0 × 10⁶ cfu.

Each data point represents log₁₀ cfu/ml results for a single mouse, with the bar showing the median for each group.

(A) Results for blood 2 h after inoculation.

(B) Results for blood 4 h after inoculation.

(C) Results for spleen homogenates 4 h after inoculation. Data is obtained from one experiment that is representative of two separate experiments.

p-Values for Mann–Whitney U comparisons between wild-type and Apcs ^−/− mice are given below the title for each panel.