Table 2 Clinical characteristics of patients.
Characteristics | Group 1 | Group 2 | Group 3 | Group 4 |
---|---|---|---|---|
Number | 20 | 4 | 5 | 5 |
Sex | ||||
Male | 15 (75%) | 3 (75%) | 3 (60%) | 3 (60%) |
Female | 5 (25%) | 1 (25%) | 2 (40%) | 2 (40%) |
Age (y) | ||||
Mean | 65 | 62 | 72 | 54.4.0 |
Range | 8–86 | 48–92 | 58–73 | 7–84 |
Extent of skin lesion | ||||
Solitary | 3 (15%) | 3 (75%) | 2 (40%) | 2 (40%) |
Generalised | 17 (85%) | 1 (25%) | 3 (60%) | 3 (60%) |
Involved extracutaneous sites | ||||
No extracutaneous involvement | 0 (0%) | 0 (100%) | 1 (20%) | 5 (100%) |
Lymph nodes | 13 (65%) | 1 (25%) | 2 (40%) | 0 (0%) |
Visceral organs | 0 (0%) | 0 (0%) | 1 (20%) | 0 (0%) |
Peripheral blood | 4 (20%) | 1 (25%) | 0 (0%) | 0 (0%) |
Bone marrow | 13 (65%) | 2 (50%) | 1 (20%) | 0 (0%) |
Palate | 3 (15%) | 0 (0%) | 2 (40%) | 0 (0%) |
Other neoplasia | 2 (10%)* | 0 (0%) | 0 (0%) | 0 (0%) |
Therapy | 0 (0%) | |||
Phototherapy | 0 (0%) | 0 (0%) | 0 (0%) | 1 (20%) |
Multiagent chemotherapy | 15 (75%) | 3 (75%) | 4 (80%) | 1 (20%) |
Radiotherapy | 2 (10%) | 1 (25%) | 1 (20%) | |
Bone marrow transplantation | 2 (10%) | 1 (25%) | 0 (0%) | 0 (0%) |
Survival, months | ||||
Median | 12 | 11 | 7 | +62 |
Range | 3–55 | 3–60 | 2–72 | |
Current status | ||||
No evidence of disease | 1 (5%) | 0 (0%) | 0 (0%) | 0 (0%) |
Alive with disease | 0 (0%) | 0 (0%) | 1 (20%) | 5 (100%) |
Died of lymphoma | 19 (95%) | 4 (100%) | 4 (80%) | 0 (0%) |
Died of other cause | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
Group 1, haematodermic neoplasm; group 2, cutaneous infiltrates of acute myeloid leukaemia; group 3, extranodal NK/T‐cell lymphoma; group 4, “classical CTCL” with expression of CD56.
*One patient developed in addition a chronic myeloid leukaemia, and another patient a myelodysplastic syndrome.