Fig. 5.
MTRR is highly expressed at E9.5 within the developing neural tube and placenta. Expression of β-galactosidase is shown in an Mtrr+/gt embryo (A) and the labyrinth layer of the Mtrr+/gt placenta (C) at E9.5, and in an Mtrr+/+ littermate embryo (B) and Mtrr+/+ placenta (D). The dams were Mtrr+/+ in all cases. b1, first brachial arch; b2, second brachial arch; op, optic eminence; ot, otic vesicle; nt, neural tube; te, telencephalon; di, diencephalon; mb, midbrain; r2, rhombomere 2; r4, rhombomere 4; da, dorsal aorta; sm, splanchnic mesoderm; he, heart; sp, spongiotrophoblast; la, labyrinth; al, allantois.