Characteristics of Go-deficient mice. (A) Body weight of littermates at 3 and 8 weeks of age. (B) Survival of 33 mice αo−/− mice at 1 week old. (C) Hot-plate tests of −/−, +/−, and +/+ mice. (D) Time elapsed between start of rotation and fall off of mice from a 4.5-cm-diameter cylinder rotating at 6 rpm. For A, C, and D, data are the mean ± SEM.