Table 2.

Mean GH (mGH) and IGF-1 at the different follow-up visits

		Visit				Difference
		Baseline	Week 12	Week 24	Week 48	Baseline – Week 48
Microadenoma
	N	8	8	8	8	8
mGH (µg/l)	Mean	5·5	1·6	1·5	1·7	−3·8
	Median	5·3	1·6	1·4	1·5	−4·1
	Min, Max	2·3, 9·1	0·5, 3·1	0·5, 2·6	0·5, 4·2	−6·7, −1·1
	SD	2·6	1·0	0·8	1·2	2·0
IGF-1 (µg/l)	Mean	570·6	210·5	194·1	218·4	−352
	Median	565·0	222·5	186·0	222·0	−344
	Min, Max	391, 720	86, 354	77, 334	95, 340	−468, −203
	SD	123·9	97·0	92·0	88·3	87·4
Macroadenoma
	N	60	60	60	60	60
mGH (µg/l)	Mean	37·4	14·3	10·9	9·0	−28·3
	Median	13·9	3·0	3·2	3·3	−9·1
	Min, Max	2, 391·2	0·5, 401·4	0·5, 245·2	0·5, 218·7	−245, 3·2
	SD	65·8	52·5	32·6	28·3	47·6
IGF-1 (µg/l)	Mean	690·3	396·2	399·2	435·6	−255
	Median	617·5	345·5	383·0	381·5	−236
	Min, Max	277, 1974	93, 818	92, 922	107, 1122	−1602, 258
	SD	287·7	199·3	192·4	248·3	296·0