Table 6.
Incidence and severity of symptoms at baseline, week 24 and week 48
| Symptom severity | Baseline N = 68 n (%) | Week 24 N = 68*n (%) | Week 48 N = 68 n (%) |
|---|---|---|---|
| Headache | |||
| Absent | 24 (35·3) | 51 (76·1) | 53 (77·9) |
| Mild | 21 (30·9) | 11 (16·4) | 10 (14·7) |
| Moderate | 15 (22·1) | 5 (7·5) | 4 (5·9) |
| Severe, not incapacitating | 7 (10·3) | 0 | 0 |
| Severe, incapacitating | 1 (1·5) | 0 | 1 (1·5) |
| Fatigue | |||
| Absent | 25 (36·8) | 46 (68·7) | 52 (76·5) |
| Mild | 23 (33·8) | 16 (23·9) | 12 (17·6) |
| Moderate | 13 (19·1) | 5 (7·5) | 3 (4·4) |
| Severe, not incapacitating | 7 (10·3) | 0 | 0 |
| Severe, incapacitating | 0 | 0 | 1 (1·5) |
| Perspiration | |||
| Absent | 20 (29·4) | 50 (74·6) | 51 (75·0) |
| Mild | 22 (32·4) | 12 (17·9) | 9 (13·2) |
| Moderate | 18 (26·5) | 3 (4·5) | 7 (10·3) |
| Severe, not incapacitating | 6 (8·8) | 2 (3·0) | 1 (1·5) |
| Severe, incapacitating | 2 (2·9) | 0 | 0 |
| Osteoarthralgia | |||
| Absent | 17 (25·0) | 35 (52·2) | 38 (55·9) |
| Mild | 18 (26·5) | 22 (32·8) | 19 (27·9) |
| Moderate | 22 (32·4) | 7 (10·4) | 6 (8·8) |
| Severe, not incapacitating | 9 (13·2) | 3 (4·5) | 5 (7·4) |
| Severe, incapacitating | 2 (2·9) | 0 | 0 |
| Carpal tunnel syndrome | |||
| Absent | 47 (69·1) | 62 (92·5) | 66 (97·1) |
| Mild | 13 (19·1) | 3 (4·5) | 0 |
| Moderate | 4 (5·9) | 1 (1·5) | 2 (2·9) |
| Severe, not incapacitating | 2 (2·9) | 1 (1·5) | 0 |
| Severe, incapacitating | 2 (2·9) | 0 | 0 |
| Paresthesia | |||
| Absent | 33 (48·5) | 61 (91·0) | 60 (88·2) |
| Mild | 19 (27·9) | 5 (7·5) | 7 (10·3) |
| Moderate | 12 (17·6) | 1 (1·5) | 1 (1·5) |
| Severe, not incapacitating | 3 (4·4) | 0 | 0 |
| Severe, incapacitating | 1 (1·5) | 0 | 0 |
*
One patient was asymptomatic at week 24.