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. Author manuscript; available in PMC: 2008 Mar 30.
Published in final edited form as: Brain Res. 2007 Jan 17;1139:163–177. doi: 10.1016/j.brainres.2006.12.095

Fig. 1.

Fig. 1

The 5-HT innervation to cerebral cortex and hippocampus is greatly diminished after neonatal injections of 5,7-DHT into the mfb. Dark-field photomicrographs illustrate the 5-HT innervation in parasagittal sections of PND 7, PND 30 and adult mice. An arrow demarcates the remaining 5-HT staining in layer IV of barrel filed cortex, where thalamocortical axons take up serotonin transiently. Note the gradual recovery of innervation in the frontal cortical areas of the PND 30 and adult compared to PND 7 5,7-DHT lesioned subject.