Fig 2.

Higher power images of the immunostained 5-HT fibers from parietal cortex at PND 7 (dark field images at 20x and bright field images at 40x) and adult parietal and frontal cortex (20x). At postnatal day 7, both serotonergic and thalamocortical axons contribute to the dense pattern of immunostaining in normal controls but in 5,7-DHT lesioned cortex serotonergic axons are depleted and thalamocortical input to the barrels remains. In the adult recovery of serotonergic axons has occurred. The axons that have regrown in the lesioned mice appear to be coarser than in the age-matched controls.