Figure 8. Effect of S-AMPA and midazolam on spinal AMPA receptor expression in naïve rats.
The AMPA receptor upregulation induced by S-AMPA (0.1 μg) was attenuated by intrathecal co-administration of S-AMPA (0.1 μg) with midazolam (10 μg) given once daily for seven days. Samples were taken on day 8. a: Western blot; b–d: statistical analysis. * P< 0.05 as compared with the S-AMPA treated group. A/M: S-AMPA+midazolam; A: S-AMPA alone.