Table 2.
Horizontal Rectus and ALR Muscle Cross-sectional Area
| Cross-sectional Area * | Innervation (Axons/mm2) | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Category | Monkey ID | Eye | Greater Directional Shrinkage (%) | Lesser Directional Shrinkage (%) | LR | Mean | P vs. Normal | MR (mm2) | Mean | P vs. Normal | ALR | Mean | P vs. Normal | LR | MR | ALR |
| Normal | RKb3 | R | 36 | 43 | 27.1 | 26.0 ± 1.0 | NA | 23.6 | 22.0 ± 5.2 | NA | 1.1 | 2.4 ± 1.1 | NA | * | * | 3.6 |
| 80478 | R | 40 | 50 | 25.2 | 16.1 | 3.0 | 36.5 | 52.7 | 7.0 | |||||||
| 94D248 | L | 57 | 50 | 25.6 | 26.1 | 3.0 | 37.4 | 33.1 | 6.0 | |||||||
| Natural | ||||||||||||||||
| esotropia | 124G | L | 29 | 31 | 29.3 | 42.4 ± 14.0 | 0.18 | 23.8 | 36.0 ± 11.0 | 0.14 | 8.0 | 6.4 ± 1.4 | 0.02 | 18.3 | 50.0 | 2.8 |
| 79434 | L | 32 | 38 | 57 | 44.8 | 5.3 | 13.4 | 13.8 | 6.6 | |||||||
| R | 17 | 29 | 40.9 | 39.7 | 5.8 | 40.2 | 18.4 | 4.3 | ||||||||
| Induced | ||||||||||||||||
| esotropia | RHn4 | L | 34 | 36 | 27.4 | 28.0 ± 1.3 | 0.12 | 25.3 | 28.6 ± 3.5 | 0.15 | 5.7 | 3.4 ± 2.1 | 0.52 | 25.0 | 52.9 | 2.4 |
| REd3 | L | 38 | 33 | 26.9 | 28.4 | 2.8 | * | * | 4.2 | |||||||
| R | 47 | 53 | 29.4 | 32.3 | 1.5 | * | * | 8.4 | ||||||||
| Exotropia | RYu6 | L | 30 | 27 | 15.3 | 16.0 ± 1.0 | 0.00 | 11.8 | 13.3 ± 2.1 | 0.09 | 2.0 | 2.0 ± 0.0 | 0.67 | 27.9 | 59.5 | 2.4 |
| R | 42 | 36 | 16.6 | 14.7 | 2.1 | 37.3 | 66.4 | 3.4 | ||||||||
*
Corrected for histologic shrinkage (mm2).