Table 3. Description of SNPs detected.
Gene | No. microarray SNPs | No. discrepant sites/ No. SNPs checked* | No. new capillary SNPs | Total No. discrepant sites | Expected heterozygosity per site |
CHRNA1 | 2 | 1/2 | 0 | 1 | 0.0002 |
CHRNB1 | 7 | 5/7 | 0 | 5 | 0.0015 |
CHRND | 11 | 4/11 | 0 | 4 | 0.0009 |
CHRNE | 25 | 7/21 | 4 | 7 | 0.0009 |
RAPSN | 10 | 1/9 | 1 | 1 | 0.0007 |
COLQ | 9 | 1/9 | 0 | 1 | 0.0007 |
CHAT | 10 | 0/10 | 0 | 0 | 0.0008 |
MUSK | 6 | 1/6 | 1 | 1 | 0.0005 |
Total | 80 | 20/75 | 6 | 20 | 0.0008 |
A total of 75 of the 80 microarray SNPs were cross-checked via capillary sequencing or electronically through the GenBank SNP database.