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. Author manuscript; available in PMC: 2008 Jun 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2007 Mar 23;221(2):251–260. doi: 10.1016/j.taap.2007.03.004

Figure 5.

Figure 5

Substrate specificity of the transport of inorganic mercury (Hg2+) as a conjugate of cysteine (Cys-S-Hg-S-Cys) in ARPE-19 cells. Cells were exposed to 5 μM Cys-S-Hg-S-Cys for 30 min at 37°C in the presence of single amino acids (A) or in the presence of two amino acids (B) under Na+-dependent or independent conditions. Each amino acid was used at a concentration of 3 mM. Results are presented as means ± standard error. Data represent two experiments performed in triplicate. *, significantly different (p < 0.05) from the mean for the control group of cells. ++, significantly (p < 0.05) from the mean for each of the two groups of cells exposed to the corresponding individual amino acids.