Table 1.
Characteristics of subjects prenatally exposed to DES and their unexposed siblings
| Subjects with prenatal DES exposure n (%) or mean (S.D.) (n=1680) | Siblings without prenatal DES exposure n (%) or mean (S.D.) (n=1447) | |
|---|---|---|
| Demographic characteristics | ||
| Duration of follow-up (years)a | 36.8 (7.4) | 36.5 (5.5) |
| Male gender | 751 (44.7)) | 781 (54.0 |
| Educational level >14 years | 1189 (71.8) | 952 (67.2) |
| Obstetric history | ||
| Definite obstetric complicationb | 1331 (79.2) | 561 (38.8) |
| Prenatal exposure to progestagen | 632 (37.6) | 281 (19.4) |
| Prenatal exposure to other hormones | 87 (5.2) | 75 (5.2) |
| History of maternal or paternal psychiatric hospitalization | 74 (4.4) | 61 (4.2) |
DES, Diethylstilboestrol; S.D., standard deviation.
a
Age of the children still alive in 2004, or age at the time of death.
b
At least one definite obstetric complication according to the Lewis and Murray scale (Lewis & Murray, 1987): threatened abortion; antepartum bleeding; severe hypertension requiring hospitalization; caesarean for emergency delivery; breech presentation; premature birth >3 weeks; postmature birth >2 weeks; birthweight <2000 g; incubator used >4 weeks.