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. Author manuscript; available in PMC: 2008 Mar 1.
Published in final edited form as: Prog Lipid Res. 2006 Dec 21;46(2):89–107. doi: 10.1016/j.plipres.2006.11.001

Table 1.

LR isoforms in three mutant models of obesity

Mutant DNA level mRNA level Protein level
LRb LRa, LRc-f
db/db mouse G → T at the region
encoding the
intracellular domain		 Abnormal splicing Absent Functional
Zucker fa/fa rat A → C at the region
encoding the
extracellular domain		 Glu → Pro codon
conversion		 Dysfunctional Functional
Koletsky f/f rat T → A at the region
encoding the
extracellular domain		 Early stop codon Absent Absent