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. Author manuscript; available in PMC: 2007 Sep 12.
Published in final edited form as: Alcohol. 2007 Mar;41(2):95–132. doi: 10.1016/j.alcohol.2007.03.003

Table 1.

Summary of biostatistical and bioinformatic analyses for individual regions and for the combined regions examining the main effect of straina

Accumbens Amygdala Frontal cortex Hippocampus Caduate-putamen Combined regions
Total significant genes (FDR < 0.10) 16 54 8 21 24 351
 iP>iNP 7 32 3 7 10 198
 iNP>iP 9 22 5 14 14 153
Minimum significant fold difference (absb) 1.37 1.18 1.39 1.21 1.19
Minimum significant fold difference (absb) 2.11 2.08 2.08 2.28 2.24
Significant genes in alcohol QTLs 2 16 2 1 8 70
Significant GO categories (P <.05) 0 0 0 0 0 12
Significant gene—gene co-citations 0 0 0 0 0 121

FDR = false discovery rate; iP = inbred alcohol—preferring rat; iNP = inbred alcoholenon-preferring rat; GO = Gene Ontology.

a

See Methods for details of each analysis.

b

Absolute value.