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IL-2 complex rapidly expands the NK compartment from immature precursors in IL-15−/− mice. (A) B6 or IL-15−/− mice received injections of IL-2 complex or IL-15 on day 0 and day 2 and spleens were analyzed on day 3. (B) Mice received congenically marked, NK1.1+CD3−-enriched splenocytes on day 0 and IL-2 complex injections on day 0 and day 2. Proliferation was measured by CFSE dilution on day 3.
