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. 2007 Sep 19;2(9):e898. doi: 10.1371/journal.pone.0000898

Table 1. Top 15 candidate housekeeping genes identified in 13,629 samples.

Gene symbol name mean SD CV (%) MFC rank
RPS13 ribosomal protein S13 12.82 0.33 2.59 1.61 1
RPL27 ribosomal protein L27 12.70 0.35 2.73 1.41 2
RPS20 ribosomal protein S20 12.81 0.37 2.90 1.67 3
RPL30 ribosomal protein L30 13.08 0.42 3.22 1.99 4
RPL13A ribosomal protein L13A 13.01 0.43 3.29 1.83 5
RPL9 ribosomal protein L9 12.95 0.44 3.36 1.68 6
SRP14 signal recognition particle 14kDa 11.45 0.40 3.46 1.48 7
RPL24 ribosomal protein L24 12.50 0.46 3.65 1.54 8
RPL22 ribosomal protein L22 11.94 0.44 3.68 1.91 9
RPS29 ribosomal protein S29 12.86 0.47 3.69 1.93 10
RPS16 ribosomal protein S16 12.48 0.47 3.73 1.62 11
RPL4 ribosomal protein L4 12.43 0.47 3.76 1.63 12
RPL6 ribosomal protein L6 12.22 0.46 3.76 1.65 13
OAZ1 ornithine decarboxylase antizyme 1 11.88 0.45 3.78 1.51 14
RPS12 ribosomal protein S12 12.90 0.49 3.82 1.99 15

CV, indicates the coefficient of variation and equals the standard deviation divided by the mean (expressed as a percentage). MFC, indicates the maximum fold change, i.e. the ratio of the maximum and minimum values observed within a dataset. The ranking is based upon three criteria: CV, a MFC<2 and a mean value lower then the maximum value with 2 standard deviation (SD) subtracted.