Table 4.
ADP sensitivity of Kir6.2-F333I/SUR channels
| SUR subtype | EC50 (μm) 2 mm Mg2+ | Slope factor 2 mm Mg2+ | A 2 mm Mg2+ |
|---|---|---|---|
| SUR1 | 50 ± 14 (n = 5) | 0.89 ± 0.21 (n = 5) | 4.2 ± 0.19 (n = 5) |
| SUR2A | 52 ± 12 (n = 6) | 0.96 ± 0.50 (n = 6) | 4.38 ± 0.53 (n = 6) |
| SUR2B | 42 ± 16 (n = 5) | 1.23 ± 0.09 (n = 5) | 4.09 ± 0.06 (n = 5) |
Mean ± s.e.m. values of the MgADP concentration producing half-maximal activation (EC50) of the channel, of the slope factor (Hill coefficient) and of the maximal current activation (A). The number of patches is indicated in parentheses.