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Insertion of 8oxodG opposite dA and dC by PolwtExo− mutant
| Km (μM) | Kcat (s−1) | (Kcat/Km)(μM−1s−1) | |
|---|---|---|---|
| dG insertion opposite dC | 1.71 × 10−3 ± 0.16 × 10−3 | 3.68 | 2.15 × 103 |
| 8oxodG insertion opposite dC | 3.27 ± 0.58 | 3.48 | 1.07 |
| 8oxodG insertion opposite dA | 9.32 ± 1.25 | 3.3 | 0.35 |
(Kcat/Km) stands for the catalytic efficiency displayed by mutant polymerase for the formation of the indicated base pair.
