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. 2007 Jul 17;35(15):4964–4976. doi: 10.1093/nar/gkm515

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© 2007 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Simulation of mutation of an endogenous and an exogenous retrovirus. Average scores for 20 sequences at each level of mutation, divided by maximum score for unmutated HIVMNCG, when analyzed with ReTe and BLAST, are shown. (a) Normalized score for sequences in the endogenous (indel) model. ReTe is more tolerant to mutation than BLAST, when scoring a sequence as retroviral. (b) Normalized score for sequences in the exogenous model. These sequences receive high scores throughout the analysis when analyzed with ReTe. BLAST, on the other hand, does not as readily recognize the sequences as descendant from HIVMNCG. Further information is given in the Supplementary Data, S1.