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Spiking [Ca2+]i activates the excitable MPF system. (A) [Ca2+]i spikes fail to induce MPF activation peaks (A) unless the cyclin synthesis requirement is met (B). τscale = 2.0, fCa = 1.44 × 10−2 min−1. (B) The injection of 0.3 mM BAPTA delays the subsequent [Ca2+]i spike (injection denoted by solid arrow) and the [Ca2+]i-induced MPF activation peak by nearly 2-fold.
