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. Author manuscript; available in PMC: 2007 Sep 17.
Published in final edited form as: Neuroscience. 2007 Apr 16;146(3):1316–1332. doi: 10.1016/j.neuroscience.2007.03.003

Fig 4.

Fig 4

Antipsychotic effects on motor function conducted during days 50-53 of treatment. Top: Water maze swim speeds measured in cm/sec. S refers to the testing session; S1= days 8-14; S2= days 22-28; S3 =days 39-45; S4 = days 84-90; S5= days 174-180 of drug treatment. Middle: Open Field Activity, left to right: horizontal activity measured as the number of photobeam breaks/5 min; Vertical activity measured as the number of photobeam breaks/5 min; stereotypical movements (repetitive photobeam breaks/ 5 min); fear/anxiety related behavior measured as the time spent in the central (C) versus the peripheral (P) zone of the activity monitor. Bottom Left: Forelimb Grip strength measured in Kg of resistance. Bottom Right: Accelerating Rotarod performance expressed as time maintained on a rotating bar that accelerated from 4 to 40 rpm over a 5-min period. The bars or points represent the mean ± S.E.M. N=12 rats/group. * = sig. different (p<0.05) from vehicle control.