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. Author manuscript; available in PMC: 2007 Sep 17.
Published in final edited form as: Neuroscience. 2007 Apr 16;146(3):1316–1332. doi: 10.1016/j.neuroscience.2007.03.003

Table 1.

Rat Behavioral Testing Protocol

Cohort Group N Treatment Day of Drug Exposure/Procedure Conducted
8-14 15 22-28 31-38 39-45 45 50-53 83-90 90 174-180 180
1 A 6 VEH OR SAC
B 6 HAL OR SAC
C 6 RISP OR SAC
2 D 12 VEH OR SAC
E 6 HAL OR SAC
F 6 RISP OR SAC
3 G 12 VEH OR SAC
H 6 HAL OR SAC
I 6 RISP OR SAC
4 J 6 VEH WM WM OR WM Motor WM SAC
K 6 HAL WM WM OR WM Motor WM SAC
L 6 RISP WM WM OR WM Motor WM SAC
5 M 6 VEH WM WM WM Motor WM WM SAC
N 6 HAL WM WM WM Motor WM WM SAC
O 6 RISP WM WM WM Motor WM WM SAC

Grp=Group; Trt=treatment; VEH = vehicle; HAL = haloperidol; RISP = risperidone; OR = object recognition; WM =water maze; SAC= sacrifice; Motor = motor function test (open field, rotor-rod, and grip strength)