Table 2. PPE complexes with peptide inhibitors.
| PDB code | Compound name | No. of amino acids | Binding subsites | Structural feature | R.m.s.d. with 2cv3† (Å) | Reference |
|---|---|---|---|---|---|---|
| 2cv3 | FR901451 | 11 | S3–S3′ | Tricyclic | — | This work |
| 1mmj | FR136706 | 5 | S5–S1′ | Linear | 0.35 | Kinoshita et al. (2003 ▶) |
| 1qr3 | FR901277 | 8 | S4–S2′ | Bicyclic | 0.30 | Nakanishi et al. (2000 ▶) |
| 1okx | Scyptolin A | 8 | S4–S1 | Monocyclic | 0.50 | Matern et al. (2003 ▶) |
| 1mcv | HEI-TOE1 | 28 | S4–S3′ | Linear, three S—S bonds | 0.50 | Aÿ et al. (2003 ▶) |
Superimpositions were performed using the Cα atoms of the proteins.