Table 2.
T-786C and E298D genotype frequency by incident coronary heart disease (CHD) or stroke case status
| Caucasian | African-American | |||||
|---|---|---|---|---|---|---|
| Genotypea | Noncases | Incident cases | P-value | Noncases | Incident cases | P-value |
| CHD | ||||||
| E298D | ||||||
| G/G | 279 (47.2%) | 365 (46.7%) | 242 (77.3%) | 182 (80.2%) | ||
| G/T + T/T | 336 (52.8%) | 416 (53.3%) | P=0.862 | 70 (22.7%) | 45 (19.8%) | P=0.437 |
| T-786C | ||||||
| T/T | 248 (42.3%) | 276 (37.4%) | 212 (68.4%) | 155 (74.9%) | ||
| T/C + C/C | 362 (57.7%) | 463 (62.7%) | P=0.079 | 91 (31.6%) | 52 (25.1%) | P=0.126 |
| Stroke | ||||||
| E298D | ||||||
| G/G | 296 (47.0%) | 70 (46.7%) | 255 (78.5%) | 86 (74.1%) | ||
| G/T + T/T | 364 (53.0%) | 80 (53.3%) | P=0.939 | 68 (21.5%) | 30 (25.9%) | P=0.362 |
| T-786C | ||||||
| T/T | 268 (42.5%) | 56 (39.2%) | 223 (69.7%) | 66 (60.6%) | ||
| T/C + C/C | 386 (57.5%) | 87 (60.8%) | P=0.466 | 90 (30.3%) | 43 (39.5%) | P=0.099 |
a
Genotype data presented as absolute (percent) genotype frequency, and weighted according to sampling fraction.