Table 5.
Effect of gomesin on the fitness of An. stephensi female mosquitoes
| Gomesin concentration (number of mosquitoes) | Survival (mean number of days ± SD) | Eggs (mean ± SD) | Larvae (mean ± SD) |
|---|---|---|---|
| 0 μM (n=31) | 23.7 ± 4.2 | 72.6 ± 34 | 43.3 ± 32.6 |
| 50 μM (n=30) | 26.9 ± 6 | 57.7 ± 23.5 | 33.9 ± 21 |
| 200 μM (n=30) | 24.9 ± 6 | 27.1* ± 15.6 | 5.5* ± 5.4 |
Female mosquitoes were membrane-fed on mouse blood containing different concentrations of gomesin and the mean and standard deviation of mosquito survival, fecundity (number of eggs) and fertility (number of larvae) were recorded. Control mosquitoes (‘0’) were artificially fed on mouse blood mixed with the same volume of 1x PBS.
Statistically significant difference of means compared to control using the Kruskal-Wallis test (p< 0.0001).