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Modulation by sinomenine of the relaxation on NE-induced vasoconstriction: pharmacology of a major constituent, sinomenine
| Sinomenine | |||||||
|---|---|---|---|---|---|---|---|
| n | 0.1 | 0.3 | 1 | 3 | 10 | 30 | 100 μM |
| 6 | 6.1 ± 2.0* | 12.5 ± 2.5** | 20.5 ± 2.2** | 25.1 ± 2.2** | 44.2 ± 4.4*** | 52.8 ± 6.0*** | 68.8 ± 5.1*** |
Values (%) represent mean ± SEM.
*P < 0.05, **P < 0.01, ***P < 0.001, with respect to control value.
