Table 1.
Daytime sleepiness | Other symptoms | MSLT | HLADQB1*0602 positivity | Low CSF hypocretin levels (<110 pg/ml) | |||
---|---|---|---|---|---|---|---|
Duration | Awaken-refreshed | Sleep latency | SOREMPS | ||||
Narcolepsy-cataplexy | short (< 30 minutes) | (+) | Cataplexy REM sleep-related symptoms | <8 min* | ≥ 2 | >90% | 85-90% >90% in HLA positive |
Narcolepsy without cataplexy | short (< 30 minutes) | (+) | Cataplexy (−) REM sleep-related symptoms | <8 min* | ≥ 2 | 40-50% | 10-20% (almost all HLA positive) |
Idiopathic hypersomnia with long sleep time | long (> 30 minutes) | (−) | Cataplexy (−) prolonged nighttime sleep (>10hrs) autonomic nervous dysfunction | <8 min* | ≤1 | no consistent results | normal |
Idiopathic hypersomnia without long sleep time | varied | (−) | Cataplexy (−) no prolonged nighttime sleep (<10hrs) autonomic nervous dysfunction | <8 min* | ≤1 | no consistent results | normal |
Less than 8 minutes is considered for both narcolepsy and idiopathic hypersomnia in the 2nd revision of ICSD.