Table 3.
Biologically annotated compound libraries
| Database | Description | Website |
|---|---|---|
| AurSCOPE | Target family-oriented knowledge database containing pharmacological and pharmacokinetical data for 160 000 GPCR ligands and 77 000 kinase inhibitors | http://www.aureus-pharma.com |
| Bioprint | Biological profile (in vitro and clinical data) of 2400 small-molecular-weight drugs and drug-like compounds | http://www.cerep.fr/ |
| ChemBank | Storage of 50 000 compounds and related biological properties in 441 high-throughput screening and small molecule microarray assays | http://chembank.broad.harvard.edu/ |
| ChemBioBase | Target centric ligand databases (GPCRs, kinases, PDE) | http://www.jubilantbiosys.com/ |
| Kinase knowledge base | kinase structure–activity and chemical synthesis data | http://www.eidogen-sertanty.com/ |
| MDL Drug Data Report | 132 000 biologically relevant compounds and well-defined derivatives | http://www.mdli.com/ |
| MedChem database | 650 000 compounds with biological and pharmacological information | http://www.gvkbio.com |
| StARLITe | Highly curated target-compound SAR relationships | http://www.inpharmatica.co.uk/ |
| Wombat | 154 236 entries over 307 700 biological activities on 1320 unique targets | http://sunsetmolecular.com/ |