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Survival curves of Swiss mice infected with T. cruzi and treated with Ru(NO)isn or Ru(NO)imN. The mice were infected with T. cruzi (Y strain, 1.0 × 102 BT per mouse) and treated with Ru(NO)isn or Ru(NO)imN (100 nmol kg−1) according to the protocol described in Table 3, (a) group 1 and (b) group 2. Another group of mice received only PBS. Data are representative of three independent experiments with similar results, n=6. Arrows indicate treatment period. PBS, phosphate-buffered saline.
