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. 2007 Jul 2;152(1):141–150. doi: 10.1038/sj.bjp.0707361

Figure 4.

Figure 4

Effect of ARL 67156 on ATP hydrolysis by NTPDases expressing cells. Activity of intact COS-7 cells transfected with NTPDase1, 2, 3 or 8 was measured in 24-well plates. Cells were preincubated 3 min with or without 100 μM ARL 67156, then the reaction was started with 100 μM ATP. (a) Human NTPDases. (b) Mouse NTPDases. The means ±s.e.m. of four independent experiments, each performed in triplicate, are shown; a star (*) indicates significant differences as evaluated by Student's t-test analysis (P-values <0.05). ARL 67156, 6-N,N-diethyl-D-β-γ-dibromomethylene adenosine triphosphate; NTPDases, nucleoside triphosphate diphosphohydrolases.