Table 4.

Adjusted OR (95% CI) from Multivariate Logistic Regression Analyses of HUNT-2 Depression, Anxiety, and Comorbid Anxiety and Depression. In the Analysis of Comorbid Anxiety and Depression, Individuals with Either Anxiety Disorders or Depression only were Excluded (See Text).

Independent variables	N	Characteristics	Depression OR (95%CI)	Anxiety OR (95% CI)	N	Anxiety & Depression OR (95% CI)
History of DIMS	21,715	−/−	Reference	Reference	19,458	Reference
	318	H1/−	1.2 (0.8–1.8)	1.6 (1.1–2.3)	262	1.4 (0.7–2.6)
	2,758	−/H2	1.8 (1.6–2.0)	3.4 (3.1–3.8)	2,134	5.8 (5.0–6.6)
	339	H1/H2	1.1 (0.8–1.6)	4.9 (3.8–6.4)	249	5.4 (3.7–7.9)
Sex	12,092	Male	Reference	Reference	10,731	Reference
	13,038	Female	0.6 (0.6–0.7)	1.7 (1.5–1.8)	11,372	1.1 (1.0–1.3)
Age group	3,810	30–39 years	Reference	Reference	3,387	Reference
	6,920	40–49 years	1.3 (1.1–1.6)	0.9 (0.8–1.0)	6,128	1.2 (0.9–1.5)
	5,990	50–59 years	1.8 (1.5–2.1)	0.6 (0.6–0.7)	5,261	1.1 (0.9–1.2)
	4,623	60–69 years	1.9 (1.6–2.3)	0.4 (0.4–0.5)	4,077	0.9 (0.7–1.1)
	3,787	70–79 years	2.7 (2.3–3.3)	0.3 (0.3–0.4)	3,250	0.8 (0.6–1.1)
Education	10,451	< 9 years	Reference	Reference	8,995	Reference
	10,301	9–12 years	0.8 (0.7–0.9)	0.9 (0.8–1.0)	9,132	0.7 (0.6–0.8)
	4,378	12 + years	0.6 (0.6–0.7)	0.8 (0.7–0.9)	3,976	0.5 (0.4–0.6)
Comorbidity	No	Reference	Reference
		N=22,414	N=22,949
	Yes	N=2,716	N=2,181
		9.4 (8.5–10.5)	9.3 (8.4–10.4)
N in the analysis		25,130	25,130		22,103