Table 2.
Mean CRP by Category
| Effect | Categories | Unadjusted Modelsa |
Adjusted Modelsa,b |
||
|---|---|---|---|---|---|
| Least squares mean (95% CI) | P-value | Least squares mean (95% CI) | P-value | ||
| Sex | M* | 2.20 (2.03, 2.39) | -- | 2.25 (2.09, 2.41) | -- |
| F | 2.96 (2.73, 3.21) | <0.0001 | 2.90 (2.69, 3.12) | <0.0001 | |
| Snoring | Rare/Occasional* | 2.23 (2.06, 2.42) | -- | 2.49 (2.31, 2.67) | -- |
| Habitual | 2.90 (2.67, 3.14) | <0.0001 | 2.65 (2.45, 2.86) | 0.25 | |
| Smoking | Never* | 2.29 (2.10, 2.48) | -- | 2.39 (2.21, 2.57) | -- |
| Past | 2.71 (2.47, 2.97) | 0.0071 | 2.58 (2.37, 2.80) | 0.18 | |
| Current | 2.97 (2.54, 3.44) | 0.0036 | 3.24 (2.83, 3.69) | 0.0001 | |
| Hypertension | No* | 2.23 (2.07, 2.40) | -- | 2.49 (2.32, 2.66) | -- |
| Yes | 3.06 (2.80, 3.34) | <0.0001 | 2.68 (2.45, 2.92) | 0.22 | |
| Diabetes | No* | 2.48 (2.33, 2.63) | -- | 2.56 (2.43, 2.70) | -- |
| Yes | 3.30 (2.66, 4.06) | 0.013 | 2.54 (2.05, 3.11) | 0.95 | |
| Exercise (hrs/week) | 0* | 3.11 (2.84, 3.40) | -- | 2.89 (2.66, 3.14) | -- |
| 1–3 | 2.17(1.89,2.47) | <0.0001 | 2.25 (1.99, 2.53) | 0.0006 | |
| 4–6 | 2.28 (2.07, 2.51) | <0.0001 | 2.45 (2.24, 2.66) | 0.0063 | |
| 7+ | 2.09 (1.66, 2.58) | 0.0006 | 2.35 (1.93, 2.83) | 0.048 | |
| Cardiovascular disease | No* | 2.50 (2.35, 2.65) | -- | 2.55 (2.42, 2.69) | -- |
| Yes | 3.01 (2.35, 3.80) | 0.15 | 2.65 (2.10, 3.30) | 0.76 | |
| APOE4 allele | Absent* | 2.52 (2.34, 2.72) | -- | 2.55 (2.39, 2.73) | -- |
| Present | 2.30 (2.03, 2.60) | 0.21 | 2.32 (2.07, 2.59) | 0.14 | |
a
Transformed CRP (log(CRP + 1)) was used for all estimates; means and 95% confidence intervals were back-transformed (exponentiated, 1 subtracted) to return estimates to original CRP units (mg/L).
b
The adjusted model for sex included age and body mass index. All other models included adjustment for sex, age, and body mass index.
*
Reference category