Table 4.
Relationship of CRP to Sleep Disordered Breathing and Sleep Duration
| Apnea-Hypopnea Index (AHI) | ||||
|---|---|---|---|---|
| Unadjuzsted Modelsa |
Adjusted Modelsa,b |
|||
| Least squares mean (95% CI) | P-value | Least squares mean (95% CI) | P-value | |
| AHI <5 | 2.32 (2.16, 2.49) | — | 2.68 (2.38, 3.00) | — |
| AHI 5-15 | 2.73 (2.40, 3.09) | 0.03 | 2.50 (2.12, 2.92) | 0.32 |
| AHI ≥ 15 | 3.51 (3.02, 4.07) | <0.0001 | 2.61 (2.17, 3.10) | 0.76 |
| Sleep Duration | ||||
| Unadjusted Modelsa |
Adjusted Modelsa,b |
|||
| Coefficient | P-value | Coefficient | P-value | |
| Total sleep time (h) | −0.003 | 0.90 | 0.004 | 0.83 |
| Usual sleep (h) | 0.012 | 0.57 | 0.028 | 0.15 |
a
The natural log of (CRP + 1) was used as the response in all models.
b
Models were adjusted for age, sex, and BMI, WHR, smoking status (current, past, never), alcoholic drinks per week, hours of exercise per week, diagnosed diabetes, hypertension (systolic ≥ 140 or diastolic ≥ 90 mmHg or antihypertensive medication), cholesterol-lowering medication and supplemental estrogen (hormone replacement therapy or oral contraceptives).