Table 1.

Morphometric analysis of different regions of interest in controls and insomniac patients. Volumes are expressed in cm³, normalized to mean total brain volume. Total brain volume was 1209±104 cm³ for controls and 1272±116 cm³ for insomniacs (W=22, P = 0.328).

Region of Interest	Good sleepers (n = 8) Mean ± SD	Patients with PI (n = 8) Mean ± SD	Wilcoxon test (two-tailed)
			W	P
Left Hippocampus	3.29 ± 0.45	2.79 ± 0.14	56	0.010
Right Hippocampus	3.64 ±0.58	3.08 ± 0.24	54	0.021
Left Amygdala	2.02 ± 0.34	1.77 ± 0.29	47	0.130
Right Amygdala	1.92 ± 0.52	1.76 ± 0.24	38	0.574
Left anterior cingulate	0.69 ± 0.44	0.43 ±0.16	44	0.234
Right anterior cingulate	0.58 ± 0.20	0.54 ± 0.22	34	0.878
Left orbitofrontal cortex	15.61 ±2.81	16.33 ±2.82	25	0.505
Right orbitofrontal cortex	17.04 ±1.75	17.37 ±3.28	29	0.798
Left dorsolateral prefrontal cortex	39.30 ± 5.22	40.38 ± 7.31	24	0.442
Right dorsolateral prefrontal cortex	39.39 ± 5.76	39.99 ± 7.31	24	0.442