Table 6.
Determinants of Most Costly Quarter OSA Patients
| a. Women with OSA (n=289) | ||||
| Univariate analysis |
Multivariate analysis |
|||
|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Age (+1 yr) | 1.05 (1.02–1.1) | 0.001 | 1.04 (1.01–1.07) | 0.047 |
| BMI (+1 kg/m2) | 1.03 (0.97–1.1) | 0.263 | 1.02 (0.95–1.08) | 0.577 |
| AHI (+1 event/hr) | 1.01 (0.99–1.02) | 0.233 | 1.001 (0.98–1.02) | 0.865 |
| CVD (1 − yes/0 − no) | 2.5 (1.5–4.4) | 0.001 | 1.7 (0.94–3.3) | 0.080 |
| Supplied antipsychotic and anxiolytic drugs (N05A, N05B) | 2.6 (1.4–4.9) | 0.002 | 2.2 (1.3–4) | 0.006 |
| Asthma (1 − yes/0 − no) | 2.2 (1.01–4.9) | 0.048 | 2.3 (1.01–5.3) | 0.048 |
| Antidepressants (NO6A) | 1.9 (1.1–3.3) | 0.024 | Not included | |
| b. Men with OSA (n=289) | ||||
| Univariate analysis |
Multivariate analysis |
|||
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Age (+1 yr) | 1.08 (1.05–1.12) | <0.0001 | 1.03 (0.99–1.1) | 0.088 |
| BMI (+1 kg/m2) | 1.04 (0.98–1.1) | 0.189 | 1.03 (0.96–1.1) | 0.384 |
| AHI (+1 event/hr) | 1.01 (0.99–1.03) | 0.090 | 1.002 (0.98–1.02) | 0.836 |
| CVD (1 − yes/0 − no) | 7.1 (3.7–13.5) | <0.0001 | 5.7 (2.7–12) | <0.0001 |
| Asthma (1 − yes/0 − no) | 3.0 (1.2–7.4) | 0.016 | 5.0 (1.7–15) | 0.003 |
| Supplied antipsychotic and anxiolytic drugs (N05A, N05B) | 4.6 (2.6–8.3) | <0.0001 | 2.5 (1.3–4.8) | 0.007 |
| Hypothyroidism (1 − yes/0 − no) | 4.8 (1.3–17.7) | 0.017 | Not included | |
| Antidepressants (NO6A) | 2.5 (1.3–4.9) | 0.006 | Not included | |
P value – comparing OSA patients to their paired matched controls.
Univariate and multiple logistic regression models were used to calculate odds ratios (ORs) with 95% confidence intervals (CI) and establish the primary determinants of most costly OSA patients.
AHI – Apnea-Hypopnea Index, BMI – body mass index, CVD – Cardiovascular Disease. The area under the receiver-operating characteristic is 70% and 80% for women and men, respectively.