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. 2007 Sep 20;117(10):2941–2951. doi: 10.1172/JCI31546

Figure 4. Removing IL-13Rα2 in IL-10–/– mice reveals a role for IL-13Rα2 in controlling goblet cell hyperplasia and mucus production.

Figure 4

Animals were sensitized and challenged as in Figure 1. Animals were euthanized 24 hours after the final airway challenge. Alcian blue–PAS staining of fixed lung sections taken from IL-10–/– (A) and IL-10–/–IL-13Rα2–/– dKO (B) mice; original magnification, ×100. Mucin-containing cells were graded as 2+ in A and 4+ in B. The inflammatory response was 8+ in both photomicrographs.