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. 2007 Sep 26;2(9):e959. doi: 10.1371/journal.pone.0000959

Figure 4. Int6 and Mek signaling interact in vivo.

Figure 4

(A–C). Only embryos treated with the 1.0 µM CI-1040, and not 0.25 µM, show a loss of posterior structures, in contrast to (D) int6 morphants (int6 MO 0.25 ng). (E, F) In combination with 0.25 µM of CI-1040, 0.25 µg of int6 MO causes a dramatic alteration of the anterior-posterior axis.