Table 2. Primary antibodies used in this study.

Antibody	Source	Working dilution
anti-Phospho-Histone H3 (ser 10) #9706	Cell Signaling Technology	1∶1000 western blot 1∶100 immunohistochemistry
anti-Phospho-p44/42 MAPK #9160	Cell Signaling Technology	1∶1000 western blot 1∶100 immunohistochemistry
anti-Int6 CN24	Watkins and Norbury, 2004	1∶500 western blot 1∶50 immunohistochemistry
anti-α-tubulin	K. Gull, Oxford	1∶5000 western blot
anti-BAX N-20	Santa Cruz Biotechnology	1∶1000 western blot
anti-MEK1 H-8	Santa Cruz Biotechnology	1∶2000 western blot
anti-actin N-20	Sigma	1∶4000 western blot