Table 2.

Treatment of early and ongoing actively induced EAN

Treatment, 2× 100 μg/day	Rats, n	Duration of treatment, days post-immunization	Mean score ± SD at disease peak	Mean T cells/mm2 ± SD in the sciatic nerve
Early
rhP2 (exp. 1)	3	4–13	0	11.3  ± 3.7*
rhP0 (exp. 1)	3	4–13	3.3  ± 0.5	347.3  ± 38.7
rhP2 (exp. 2)	3	4–13	0	10.6  ± 2.8*
rhP0 (exp. 2)	3	4–13	5.7  ± 1.9	359.7  ± 41.7
Ongoing
rhP2	3	13–18	3.8  ± 2.9†	95.7  ± 25.7*
rhP0	3	13–18	6.5  ± 0.4	360.2  ± 32.2

Exp., experiment. 

^*P < 0.01 vs rhP0;  

^†P < 0.05 vs. rhP0.