Table 1.

Cytotoxic functions of CD8⁺ bulk TIL cultures derived from two metastatic lesions, abdomen (AB) and shoulder (SH), and of eight clones derived from AB-TIL

Effector cells	% lysis of autologous melanoma*	% lysis of K562	% lysis of Daudi	TCRAV usage	TCRBV usage
CD8+ AB-TIL	100	75	45	—	—
CD8+ SH-TIL	82	87	38	—	—
Clone AB-1	100	2	0	TCRAV1	TCRBV2
AB-2	81	1	2	TCRAV1	TCRBV2
AB-3	54	1	0	TCRAV1	TCRBV2
AB-4	31	0	0	TCRAV8 TCRAV16	TCRBV20
AB-5	27	0	2	TCRAV8 TCRAV16	TCRBV20
AB-6	22	1	2	TCRAV8 TCRAV16	TCRBV20
AB-7	29	3	0	TCRAV11 TCRAV16	TCRBV11
AB-8	3	4	9	TCRAV3	TCRBV7

The table shows the TCRAV and TCRBV gene usage by these clones. 

^*Percent lysis at 50:1 (effector-to-target) ratio.