Figure 2.

Sequences of Q region genes match either the 5′ (left half) or 3′ (right half) region of the bm28 mutation cluster, but no single gene in the Q region matches the entire mutation. We hybridized the BamHI-digested cosmids representing the H-2^b K and D/Q region genes with oligonucleotide probes that were specific for the left (D^bm28-97/99–1) or right (D^bm28-103) half of the mutation cluster. Multiple genes from the Q region contain nucleotides in common with bm28 codons 97 and 99 (Left), and Q2 contains the single nucleotide match with bm28 codon 103 (Right).