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. 1997 Feb 18;94(4):1465–1470. doi: 10.1073/pnas.94.4.1465

Figure 1.

Figure 1

Comparison of the PBS in the N-CAM promoter to a consensus binding sequence for Pax-6. The TGCTCC motifs comprising PBS-1 and PBS-2 are highlighted within a box. Homology between the PBS and a Pax-6 consensus sequence selected from random oligonucleotides (20) is indicated by vertical lines. Base pair substitutions in the mutant probes PBS/DM, PBS-1/3M, and PBS-2/3M are shown in boxes. PBS/DM contained mutations in both PBS-1 and PBS-2, PBS-1/3M had three mutations in PBS-1, and PBS-2/3M contained three mutations in PBS-2.