Figure 5.

Model for positioning of a molecule of linker histone on the core particle. The globular domain is presented by a solid circle, and the N- and C-terminal tails are presented as unstructured stretches. The portions of linker DNA protected by LH binding are marked. The numbers denote the number of helical turns of the DNA, with 0 denoting the dyad axis. Two alternative off-axis locations of the LH are depicted. The C-terminal tail of the LH is drawn as simultaneously interacting with the entering and exiting DNA helices to form the stem structure recently described by Hamiche et al. (32).